pentobarbital will minimize the extent or impact of iloperidone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.pentobarbital will decrease the level or effect of phenytoin by influencing hepatic enzyme CYP2C9/10 metabolism. Use Caution/Watch.benzhydrocodone/acetaminophen and pentobarbital both increase sedation. Keep aw